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The complex of wild type B-RAF and BAY439006

Contents 1 Introduction 2 Structure 3 Regulation 4 Other Inhibitors 5 Aplications in Medicine 6 External Ressources 7 References 8 Protreopedia Page Contributors and Editors

Introduction

Structure

spinqualitylabelsall models 3D View of the complex Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Blablastructurepdb^[1]

Regulation

Other Inhibitors

Aplications in Medicine

External Ressources

PDB file for 1UWH

References

1. ↑ Wan PT, Garnett MJ, Roe SM, Lee S, Niculescu-Duvaz D, Good VM, Jones CM, Marshall CJ, Springer CJ, Barford D, Marais R. Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF. Cell. 2004 Mar 19;116(6):855-67. PMID:15035987

Protreopedia Page Contributors and Editors

Kostika Sofroni and Gilles Dupouy