1upf

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Image:1upf.png

Template:STRUCTURE 1upf

STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE, MUTANT C128V BOUND TO THE DRUG 5-FLUOROURACIL

Template:ABSTRACT PUBMED 9628859

About this Structure

1UPF is a 4 chains structure of sequences from Toxoplasma gondii. Full crystallographic information is available from OCA.

Reference

  • Schumacher MA, Carter D, Scott DM, Roos DS, Ullman B, Brennan RG. Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding. EMBO J. 1998 Jun 15;17(12):3219-32. PMID:9628859 doi:http://dx.doi.org/10.1093/emboj/17.12.3219

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