1uwj

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Image:1uwj.png

Template:STRUCTURE 1uwj

THE COMPLEX OF MUTANT V599E B-RAF AND BAY439006

Template:ABSTRACT PUBMED 15035987

About this Structure

1uwj is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wan PT, Garnett MJ, Roe SM, Lee S, Niculescu-Duvaz D, Good VM, Jones CM, Marshall CJ, Springer CJ, Barford D, Marais R. Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF. Cell. 2004 Mar 19;116(6):855-67. PMID:15035987

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