1x2r

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Template:STRUCTURE 1x2r

Structural basis for the defects of human lung cancer somatic mutations in the repression activity of Keap1 on Nrf2

Template:ABSTRACT PUBMED 16507366

About this Structure

1x2r is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

• Padmanabhan B, Tong KI, Ohta T, Nakamura Y, Scharlock M, Ohtsuji M, Kang MI, Kobayashi A, Yokoyama S, Yamamoto M. Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer. Mol Cell. 2006 Mar 3;21(5):689-700. PMID:16507366 doi:10.1016/j.molcel.2006.01.013