2b0m

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Template:STRUCTURE 2b0m

Human dihydroorotate dehydrogenase bound to a novel inhibitor

Template:ABSTRACT PUBMED 16406782

About this Structure

2B0M is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hurt DE, Sutton AE, Clardy J. Brequinar derivatives and species-specific drug design for dihydroorotate dehydrogenase. Bioorg Med Chem Lett. 2006 Mar 15;16(6):1610-5. Epub 2006 Jan 10. PMID:16406782 doi:S0960-894X(05)01599-4

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