2aot

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Template:STRUCTURE 2aot

Contents

Histamine Methyltransferase Complexed with the Antihistamine Drug Diphenhydramine

Template:ABSTRACT PUBMED 16168438

Disease

Known disease associated with this structure: Asthma, susceptibility to OMIM:[605238]

About this Structure

2AOT is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Horton JR, Sawada K, Nishibori M, Cheng X. Structural basis for inhibition of histamine N-methyltransferase by diverse drugs. J Mol Biol. 2005 Oct 21;353(2):334-44. PMID:16168438 doi:10.1016/j.jmb.2005.08.040

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