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2gll

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Revision as of 10:51, 7 January 2013 by OCA (Talk | contribs)
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Image:2gll.png

Template:STRUCTURE 2gll

Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase(FabZ) from Helicobacter pylori

Template:ABSTRACT PUBMED 18093984

About this Structure

2gll is a 6 chain structure with sequence from Helicobacter pylori. Full crystallographic information is available from OCA.

Reference

  • Zhang L, Liu W, Hu T, Du L, Luo C, Chen K, Shen X, Jiang H. Structural basis for catalytic and inhibitory mechanisms of beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ). J Biol Chem. 2008 Feb 29;283(9):5370-9. Epub 2007 Dec 19. PMID:18093984 doi:10.1074/jbc.M705566200
  • He L, Zhang L, Liu X, Li X, Zheng M, Li H, Yu K, Chen K, Shen X, Jiang H, Liu H. Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination. J Med Chem. 2009 Apr 23;52(8):2465-81. PMID:19309082 doi:10.1021/jm8015602

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