2kri

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Template:STRUCTURE 2kri

Contents

Structure of a complex between domain V of beta2-glycoprotein I and the fourth ligand-binding module from LDLR determined with Haddock

Template:ABSTRACT PUBMED 20223219

Disease

Known disease associated with this structure: Hypercholesterolemia, familial OMIM:[606945]

About this Structure

2KRI is a 2 chains structure with sequences from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Lee CJ, De Biasio A, Beglova N. Mode of interaction between beta2GPI and lipoprotein receptors suggests mutually exclusive binding of beta2GPI to the receptors and anionic phospholipids. Structure. 2010 Mar 10;18(3):366-76. PMID:20223219 doi:10.1016/j.str.2009.12.013

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