2k21

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Image:2k21.jpg

Template:STRUCTURE 2k21

Contents

NMR structure of human KCNE1 in LMPG micelles at pH 6.0 and 40 degree C

Template:ABSTRACT PUBMED 18611041

Disease

Known disease associated with this structure: Jervell and Lange-Nielsen syndrome 2 OMIM:[176261], Long QT syndrome-5 OMIM:[176261]

About this Structure

2K21 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Structure of KCNE1 and implications for how it modulates the KCNQ1 potassium channel., Kang C, Tian C, Sonnichsen FD, Smith JA, Meiler J, George AL Jr, Vanoye CG, Kim HJ, Sanders CR, Biochemistry. 2008 Aug 5;47(31):7999-8006. Epub 2008 Jul 9. PMID:18611041

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