2nup

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Template:STRUCTURE 2nup

Contents

Crystal Structure of the human Sec23a/24a heterodimer, complexed with the SNARE protein Sec22b

Template:ABSTRACT PUBMED 17499046

Disease

Known disease associated with this structure: Craniolenticulosutural dysplasia OMIM:[610511]

About this Structure

2NUP is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Mancias JD, Goldberg J. The transport signal on Sec22 for packaging into COPII-coated vesicles is a conformational epitope. Mol Cell. 2007 May 11;26(3):403-14. PMID:17499046 doi:10.1016/j.molcel.2007.03.017

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