2gox

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Image:2gox.png

Template:STRUCTURE 2gox

Contents

Crystal structure of Efb-C / C3d Complex

Template:ABSTRACT PUBMED 17351618

Disease

Known disease associated with this structure: C3 deficiency OMIM:[120700], Macular degeneration, age-related, 9 OMIM:[120700]

About this Structure

2GOX is a 4 chains structure of sequences from Homo sapiens and Staphylococcus aureus. Full crystallographic information is available from OCA.

Reference

  • Hammel M, Sfyroera G, Ricklin D, Magotti P, Lambris JD, Geisbrecht BV. A structural basis for complement inhibition by Staphylococcus aureus. Nat Immunol. 2007 Apr;8(4):430-7. Epub 2007 Mar 11. PMID:17351618 doi:10.1038/ni1450

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