2goo

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Image:2goo.png

Template:STRUCTURE 2goo

Contents

Ternary Complex of BMP-2 bound to BMPR-Ia-ECD and ActRII-ECD

Template:ABSTRACT PUBMED 16672363

Disease

Known disease associated with this structure: HFE hemochromatosis, modifier of OMIM:[112261], Juvenile polyposis syndrome, infantile form OMIM:[601299], Polyposis syndrome, hereditary mixed, 2 OMIM:[601299], Polyposis, juvenile intestinal OMIM:[601299]

About this Structure

2GOO is a 6 chains structure of sequences from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Allendorph GP, Vale WW, Choe S. Structure of the ternary signaling complex of a TGF-beta superfamily member. Proc Natl Acad Sci U S A. 2006 May 16;103(20):7643-8. Epub 2006 May 3. PMID:16672363

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