2j50
From Proteopedia
STRUCTURE OF AURORA-2 IN COMPLEX WITH PHA-739358
Template:ABSTRACT PUBMED 17125279
About this Structure
2j50 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Fancelli D, Moll J, Varasi M, Bravo R, Artico R, Berta D, Bindi S, Cameron A, Candiani I, Cappella P, Carpinelli P, Croci W, Forte B, Giorgini ML, Klapwijk J, Marsiglio A, Pesenti E, Rocchetti M, Roletto F, Severino D, Soncini C, Storici P, Tonani R, Zugnoni P, Vianello P. 1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: identification of a potent Aurora kinase inhibitor with a favorable antitumor kinase inhibition profile. J Med Chem. 2006 Nov 30;49(24):7247-51. PMID:17125279 doi:10.1021/jm060897w
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Berta, D. | Bindi, S. | Cameron, A D. | Fancelli, D. | Forte, B. | Izzo, G. | Rusconi, L. | Severino, D. | Storici, P. | Tonani, R. | Varasi, M. | Vianello, P. | Atp-binding | Cell cycle | Kinase | Nucleotide- binding | Nucleotide-binding | Phosphorylation | Serine-threonine-protein kinase | Serine/threonine-protein kinase | Transferase
