2jk7

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Image:2jk7.png

Template:STRUCTURE 2jk7

XIAP BIR3 BOUND TO A SMAC MIMETIC

Template:ABSTRACT PUBMED 18954041

About this Structure

2jk7 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Sun H, Stuckey JA, Nikolovska-Coleska Z, Qin D, Meagher JL, Qiu S, Lu J, Yang CY, Saito NG, Wang S. Structure-Based Design, Synthesis, Evaluation, and Crystallographic Studies of Conformationally Constrained Smac Mimetics as Inhibitors of the X-linked Inhibitor of Apoptosis Protein (XIAP). J Med Chem. 2008 Oct 28. PMID:18954041 doi:10.1021/jm8006849

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