2fju

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Image:2fju.png

Template:STRUCTURE 2fju

Contents

Activated Rac1 bound to its effector phospholipase C beta 2

Template:ABSTRACT PUBMED 17115053

Disease

Known disease associated with this structure: Platelet PLC beta-2 deficiency OMIM:[604114]

About this Structure

2FJU is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Jezyk MR, Snyder JT, Gershberg S, Worthylake DK, Harden TK, Sondek J. Crystal structure of Rac1 bound to its effector phospholipase C-beta2. Nat Struct Mol Biol. 2006 Dec;13(12):1135-40. Epub 2006 Nov 19. PMID:17115053 doi:http://dx.doi.org/10.1038/nsmb1175

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