2isg

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Image:2isg.png

Template:STRUCTURE 2isg

Botulinum Neurotoxin A Light Chain WT Crystal Form B

Template:ABSTRACT PUBMED 17092934

About this Structure

2ISG is a 2 chains structure of sequences from Clostridium botulinum. Full crystallographic information is available from OCA.

Reference

  • Burnett JC, Ruthel G, Stegmann CM, Panchal RG, Nguyen TL, Hermone AR, Stafford RG, Lane DJ, Kenny TA, McGrath CF, Wipf P, Stahl AM, Schmidt JJ, Gussio R, Brunger AT, Bavari S. Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons. J Biol Chem. 2007 Feb 16;282(7):5004-14. Epub 2006 Nov 8. PMID:17092934 doi:10.1074/jbc.M608166200

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