2ka6

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Image:2ka6.png

Template:STRUCTURE 2ka6

Contents

NMR structure of the CBP-TAZ2/STAT1-TAD complex

Template:ABSTRACT PUBMED 19214187

Disease

Known disease associated with this structure: Mycobacterial infection, atypical, familial disseminated OMIM:[600555], STAT1 deficiency, complete OMIM:[600555]

About this Structure

2KA6 is a 2 chains structure with sequences from Homo sapiens and Mus musculus. The February 2010 RCSB PDB Molecule of the Month feature on Enhanceosome by David Goodsell is 10.2210/rcsb_pdb/mom_2010_2. Full crystallographic information is available from OCA.

Reference

  • Wojciak JM, Martinez-Yamout MA, Dyson HJ, Wright PE. Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains. EMBO J. 2009 Apr 8;28(7):948-58. Epub 2009 Feb 12. PMID:19214187 doi:10.1038/emboj.2009.30

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