2z4o

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Image:2z4o.png

Template:STRUCTURE 2z4o

Wild Type HIV-1 Protease with potent Antiviral inhibitor GRL-98065

Template:ABSTRACT PUBMED 17696515

About this Structure

2Z4O is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Wang YF, Tie Y, Boross PI, Tozser J, Ghosh AK, Harrison RW, Weber IT. Potent new antiviral compound shows similar inhibition and structural interactions with drug resistant mutants and wild type HIV-1 protease. J Med Chem. 2007 Sep 6;50(18):4509-15. Epub 2007 Aug 16. PMID:17696515 doi:10.1021/jm070482q

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