2xch

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Image:2xch.png

Template:STRUCTURE 2xch

CRYSTAL STRUCTURE OF PDK1 IN COMPLEX WITH A PYRAZOLOQUINAZOLINE INHIBITOR

Template:ABSTRACT PUBMED 20621725

About this Structure

2xch is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Angiolini M, Banfi P, Casale E, Casuscelli F, Fiorelli C, Saccardo MB, Silvagni M, Zuccotto F. Structure-based optimization of potent PDK1 inhibitors. Bioorg Med Chem Lett. 2010 Jul 15;20(14):4095-9. Epub 2010 Jun 8. PMID:20621725 doi:10.1016/j.bmcl.2010.05.070

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