3bea

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Template:STRUCTURE 3bea

cFMS tyrosine kinase (tie2 KID) in complex with a pyrimidinopyridone inhibitor

Template:ABSTRACT PUBMED 18342505

About this Structure

3BEA is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Huang H, Hutta DA, Hu H, DesJarlais RL, Schubert C, Petrounia IP, Chaikin MA, Manthey CL, Player MR. Design and synthesis of a pyrido[2,3-d]pyrimidin-5-one class of anti-inflammatory FMS inhibitors. Bioorg Med Chem Lett. 2008 Apr 1;18(7):2355-61. Epub 2008 Mar 4. PMID:18342505 doi:10.1016/j.bmcl.2008.02.070

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