2vo6

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Image:2vo6.png

Template:STRUCTURE 2vo6

STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH 4-(4-CHLOROBENZYL)-1-(7H-PYRROLO(2,3-D)PYRIMIDIN-4-YL)PIPERIDIN-4-YLAMINE

Template:ABSTRACT PUBMED 18345609

About this Structure

2VO6 is a 2 chains structure of sequences from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Caldwell JJ, Davies TG, Donald A, McHardy T, Rowlands MG, Aherne GW, Hunter LK, Taylor K, Ruddle R, Raynaud FI, Verdonk M, Workman P, Garrett MD, Collins I. Identification of 4-(4-Aminopiperidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidines as Selective Inhibitors of Protein Kinase B through Fragment Elaboration. J Med Chem. 2008 Apr 10;51(7):2147-57. Epub 2008 Mar 18. PMID:18345609 doi:10.1021/jm701437d

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