3bps
From Proteopedia
Contents |
PCSK9:EGF-A complex
Template:ABSTRACT PUBMED 18250299
Disease
Known disease associated with this structure: Hypercholesterolemia, familial OMIM:[606945]
About this Structure
3BPS is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Kwon HJ, Lagace TA, McNutt MC, Horton JD, Deisenhofer J. Molecular basis for LDL receptor recognition by PCSK9. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1820-5. Epub 2008 Feb 4. PMID:18250299
Page seeded by OCA on Tue Feb 17 00:33:47 2009
Categories: Homo sapiens | Kwon, H J. | Alternative splicing | Autocatalytic cleavage | Calcium | Cholesterol metabolism | Coated pit | Disease mutation | Egf-like domain | Endocytosis | Glycoprotein | Host-virus interaction | Hydrolase | Hydrolase/lipid transport complex | Ldl receptor | Lipid metabolism | Lipid transport | Membrane | Pcsk9 | Phosphoprotein | Polymorphism | Protease | Secreted | Serine protease | Steroid metabolism | Transmembrane | Transport | Zymogen