2w1i
From Proteopedia
STRUCTURE DETERMINATION OF AURORA KINASE IN COMPLEX WITH INHIBITOR
Template:ABSTRACT PUBMED 19143567
About this Structure
2W1I is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Howard S, Berdini V, Boulstridge JA, Carr MG, Cross DM, Curry J, Devine LA, Early TR, Fazal L, Gill AL, Heathcote M, Maman S, Matthews JE, McMenamin RL, Navarro EF, O'Brien MA, O'Reilly M, Rees DC, Reule M, Tisi D, Williams G, Vinkovic M, Wyatt PG. Fragment-based discovery of the pyrazol-4-yl urea (AT9283), a multitargeted kinase inhibitor with potent aurora kinase activity. J Med Chem. 2009 Jan 22;52(2):379-88. PMID:19143567 doi:10.1021/jm800984v
Page seeded by OCA on Wed Jan 28 09:39:15 2009
Categories: Homo sapiens | Non-specific protein-tyrosine kinase | Berdini, V. | Boulstridge, J A. | Brien, M A.O. | Carr, M G. | Cross, D M. | Curry, J. | Devine, L A. | Early, T R. | Fazal, L. | Gill, A L. | Heathcote, M. | Howard, S. | Maman, S. | Matthews, J E. | Mcmenamin, R L. | Navarro, E F. | Rees, D C. | Reilly, M O. | Reule, M. | Tisi, D. | Vinkovic, M. | Williams, G. | Wyatt, P G. | Atp-binding | Aurora | Cancer | Chromosomal rearrangement | Disease mutation | Inhibitor | Kinase | Membrane | Nucleotide-binding | Phosphoprotein | Polymorphism | Proto-oncogene | Sh2 domain | Transferase | Tyrosine-protein kinase
