2qtz

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Image:2qtz.png

Template:STRUCTURE 2qtz

Contents

Crystal Structure of the NADP+-bound FAD-containing FNR-like Module of Human Methionine Synthase Reductase

Template:ABSTRACT PUBMED 17892308

Disease

Known disease associated with this structure: Homocystinuria-megaloblastic anemia, cbl E type OMIM:[602568], Neural tube defects, folate-sensitive, susceptibility to OMIM:[602568]

About this Structure

2QTZ is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wolthers KR, Lou X, Toogood HS, Leys D, Scrutton NS. Mechanism of coenzyme binding to human methionine synthase reductase revealed through the crystal structure of the FNR-like module and isothermal titration calorimetry. Biochemistry. 2007 Oct 23;46(42):11833-44. Epub 2007 Sep 25. PMID:17892308 doi:10.1021/bi701209p

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