2qtw
From Proteopedia
The Crystal Structure of PCSK9 at 1.9 Angstroms Resolution Reveals structural homology to Resistin within the C-terminal domain
Template:ABSTRACT PUBMED 17804797
About this Structure
2qtw is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Hampton EN, Knuth MW, Li J, Harris JL, Lesley SA, Spraggon G. The self-inhibited structure of full-length PCSK9 at 1.9 A reveals structural homology with resistin within the C-terminal domain. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14604-9. Epub 2007 Sep 5. PMID:17804797
Categories: Homo sapiens | Hampton, E N. | Harris, J L. | Knuth, M W. | Lesley, S A. | Li, J. | Spraggon, G. | Autocatalytic cleavage | Cholesterol metabolism | Coronary heart disease | Disease mutation | Glycoprotein | Hydrolase | Hypercholesterolemia | Lipid metabolism | Low density lipoprotein receptor | Phosphorylation | Pro-protein convertase | Protease | Secreted | Serine protease | Steroid metabolism | Zymogen
