1y8j

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Image:1y8j.gif

1y8j, resolution 2.25Å

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Crystal Structure of human NEP complexed with an imidazo[4,5-c]pyridine inhibitor

Disease

Known diseases associated with this structure: Membranous glomerulonephritis, antenatal OMIM:[120520], Neutral endopeptidase deficiency OMIM:[120520], Schizophrenia, susceptibility to OMIM:[607265]

About this Structure

1Y8J is a Single protein structure of sequence from Homo sapiens with NAG, ZN, ACT and STS as ligands. Active as Neprilysin, with EC number 3.4.24.11 Full crystallographic information is available from OCA.

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