3e0p

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Image:3e0p.png

Template:STRUCTURE 3e0p

The X-ray structure of Human Prostasin in complex with a covalent benzoxazole inhibitor

Template:ABSTRACT PUBMED 18752942

About this Structure

3E0P is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Tully DC, Vidal A, Chatterjee AK, Williams JA, Roberts MJ, Petrassi HM, Spraggon G, Bursulaya B, Pacoma R, Shipway A, Schumacher AM, Danahay H, Harris JL. Discovery of inhibitors of the channel-activating protease prostasin (CAP1/PRSS8) utilizing structure-based design. Bioorg Med Chem Lett. 2008 Nov 15;18(22):5895-9. Epub 2008 Aug 14. PMID:18752942 doi:10.1016/j.bmcl.2008.08.029

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