3du8

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Image:3du8.jpg

Template:STRUCTURE 3du8

Crystal structure of GSK-3 beta in complex with NMS-869553A

Template:ABSTRACT PUBMED 19115845

About this Structure

3DU8 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Menichincheri M, Bargiotti A, Berthelsen J, Bertrand JA, Bossi R, Ciavolella A, Cirla A, Cristiani C, Croci V, D'Alessio R, Fasolini M, Fiorentini F, Forte B, Isacchi A, Martina K, Molinari A, Montagnoli A, Orsini P, Orzi F, Pesenti E, Pezzetta D, Pillan A, Poggesi I, Roletto F, Scolaro A, Tato M, Tibolla M, Valsasina B, Varasi M, Volpi D, Santocanale C, Vanotti E. First Cdc7 kinase inhibitors: pyrrolopyridinones as potent and orally active antitumor agents. 2. Lead discovery. J Med Chem. 2009 Jan 22;52(2):293-307. PMID:19115845 doi:10.1021/jm800977q

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