3ekn
From Proteopedia
Insulin receptor kinase complexed with an inhibitor
Template:ABSTRACT PUBMED 19071018
About this Structure
3EKN is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Chamberlain SD, Redman AM, Wilson JW, Deanda F, Shotwell JB, Gerding R, Lei H, Yang B, Stevens KL, Hassell AM, Shewchuk LM, Leesnitzer MA, Smith JL, Sabbatini P, Atkins C, Groy A, Rowand JL, Kumar R, Mook RA Jr, Moorthy G, Patnaik S. Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity. Bioorg Med Chem Lett. 2009 Jan 15;19(2):360-4. Epub 2008 Nov 24. PMID:19071018 doi:S0960-894X(08)01461-3
Page seeded by OCA on Wed Sep 22 11:42:08 2010
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Atkins, C. | Chamberlain, S. | Deanda, F. | Dumble, M. | Gerding, R. | Groy, A. | Korenchuk, S. | Kumar, R. | Lei, H. | Mook, R. | Moorthy, G. | Redman, A. | Rowland, J. | Shewchuk, L. | Alternative splicing | Atp-binding | Carbohydrate metabolism | Cleavage on pair of basic residue | Diabetes mellitus | Disease mutation | Glycoprotein | Insulin | Kinase | Membrane | Nucleotide-binding | Phosphoprotein | Polymorphism | Receptor | Transferase | Transmembrane | Tyrosine kinase | Tyrosine-protein kinase
