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2f8p

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Revision as of 18:33, 14 March 2011 by OCA (Talk | contribs)
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Image:2f8p.png

Template:STRUCTURE 2f8p

Crystal structure of obelin following Ca2+ triggered bioluminescence suggests neutral coelenteramide as the primary excited state

Template:ABSTRACT PUBMED 16467137

About this Structure

2f8p is a 1 chain structure with sequence from Obelia longissima. Full crystallographic information is available from OCA.

Reference

  • Liu ZJ, Stepanyuk GA, Vysotski ES, Lee J, Markova SV, Malikova NP, Wang BC. Crystal structure of obelin after Ca2+-triggered bioluminescence suggests neutral coelenteramide as the primary excited state. Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2570-5. Epub 2006 Feb 8. PMID:16467137
  • Liu ZJ, Vysotski ES, Chen CJ, Rose JP, Lee J, Wang BC. Structure of the Ca2+-regulated photoprotein obelin at 1.7 A resolution determined directly from its sulfur substructure. Protein Sci. 2000 Nov;9(11):2085-93. PMID:11152120
  • Deng L, Vysotski ES, Liu ZJ, Markova SV, Malikova NP, Lee J, Rose J, Wang BC. Structural basis for the emission of violet bioluminescence from a W92F obelin mutant. FEBS Lett. 2001 Oct 12;506(3):281-5. PMID:11602262
  • Vysotski ES, Liu ZJ, Markova SV, Blinks JR, Deng L, Frank LA, Herko M, Malikova NP, Rose JP, Wang BC, Lee J. Violet bioluminescence and fast kinetics from W92F obelin: structure-based proposals for the bioluminescence triggering and the identification of the emitting species. Biochemistry. 2003 May 27;42(20):6013-24. PMID:12755603 doi:10.1021/bi027258h
  • Liu ZJ, Vysotski ES, Deng L, Lee J, Rose J, Wang BC. Atomic resolution structure of obelin: soaking with calcium enhances electron density of the second oxygen atom substituted at the C2-position of coelenterazine. Biochem Biophys Res Commun. 2003 Nov 14;311(2):433-9. PMID:14592432
  • Deng L, Markova SV, Vysotski ES, Liu ZJ, Lee J, Rose J, Wang BC. Crystal structure of a Ca2+-discharged photoprotein: implications for mechanisms of the calcium trigger and bioluminescence. J Biol Chem. 2004 Aug 6;279(32):33647-52. Epub 2004 May 20. PMID:15155735 doi:10.1074/jbc.M402427200

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