2nsq

From Proteopedia

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Template:STRUCTURE 2nsq

Crystal structure of the C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein

Template:ABSTRACT PUBMED 11840194

About this Structure

2nsq is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Chen H, Ross CA, Wang N, Huo Y, MacKinnon DF, Potash JB, Simpson SG, McMahon FJ, DePaulo Jr JR, McInnis MG. NEDD4L on human chromosome 18q21 has multiple forms of transcripts and is a homologue of the mouse Nedd4-2 gene. Eur J Hum Genet. 2001 Dec;9(12):922-30. PMID:11840194 doi:10.1038/sj.ejhg.5200747
• Ichimura T, Yamamura H, Sasamoto K, Tominaga Y, Taoka M, Kakiuchi K, Shinkawa T, Takahashi N, Shimada S, Isobe T. 14-3-3 proteins modulate the expression of epithelial Na+ channels by phosphorylation-dependent interaction with Nedd4-2 ubiquitin ligase. J Biol Chem. 2005 Apr 1;280(13):13187-94. Epub 2005 Jan 26. PMID:15677482 doi:10.1074/jbc.M412884200
• Winberg G, Matskova L, Chen F, Plant P, Rotin D, Gish G, Ingham R, Ernberg I, Pawson T. Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine kinases. Mol Cell Biol. 2000 Nov;20(22):8526-35. PMID:11046148
• Snyder PM, Olson DR, Thomas BC. Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel. J Biol Chem. 2002 Jan 4;277(1):5-8. Epub 2001 Nov 5. PMID:11696533 doi:10.1074/jbc.C100623200
• Harvey KF, Shearwin-Whyatt LM, Fotia A, Parton RG, Kumar S. N4WBP5, a potential target for ubiquitination by the Nedd4 family of proteins, is a novel Golgi-associated protein. J Biol Chem. 2002 Mar 15;277(11):9307-17. Epub 2001 Dec 17. PMID:11748237 doi:10.1074/jbc.M110443200