3ezg

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Image:3ezg.png

Template:STRUCTURE 3ezg

Contents

Crystal structure of E18Q DJ-1 with oxidized C106

Template:ABSTRACT PUBMED 19124468

Disease

Known disease associated with this structure: Amyotrophic lateral sclerosis-Parkinsonism/dementia complex 2 OMIM:[602533], Parkinson disease 7, autosomal recessive early-onset OMIM:[602533]

About this Structure

3EZG is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Blackinton J, Lakshminarasimhan M, Thomas KJ, Ahmad R, Greggio E, Raza AS, Cookson MR, Wilson MA. Formation of a stabilized cysteine sulfinic acid is critical for the mitochondrial function of the parkinsonism protein DJ-1. J Biol Chem. 2009 Mar 6;284(10):6476-85. Epub 2009 Jan 5. PMID:19124468 doi:http://dx.doi.org/10.1074/jbc.M806599200

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