2aaq

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Image:2aaq.gif

2aaq, resolution 2.60Å

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Crystal Structure Analysis of the human Glutahione Reductase, complexed with GoPI

Disease

Known disease associated with this structure: Hemolytic anemia due to glutathione reductase deficiency OMIM:[138300]

About this Structure

2AAQ is a Single protein structure of sequence from Homo sapiens with PO4, CL, K, FAD, AUP, AU and GOL as ligands. Active as Glutathione-disulfide reductase, with EC number 1.8.1.7 Full crystallographic information is available from OCA.

Reference

Undressing of phosphine gold(I) complexes as irreversible inhibitors of human disulfide reductases., Urig S, Fritz-Wolf K, Reau R, Herold-Mende C, Toth K, Davioud-Charvet E, Becker K, Angew Chem Int Ed Engl. 2006 Mar 13;45(12):1881-6. PMID:16493712

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