3g3e

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Image:3g3e.jpg

Template:STRUCTURE 3g3e

Crystal structure of human D-amino acid oxidase in complex with hydroxyquinolin-2(1H)

Template:ABSTRACT PUBMED 19438227

About this Structure

3G3E is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Duplantier AJ, Becker SL, Bohanon MJ, Borzilleri KA, Chrunyk BA, Downs JT, Hu LY, El-Kattan A, James LC, Liu S, Lu J, Maklad N, Mansour MN, Mente S, Piotrowski MA, Sakya SM, Sheehan S, Steyn SJ, Strick CA, Williams VA, Zhang L. Discovery, SAR, and pharmacokinetics of a novel 3-Hydroxyquinolin-2(1H)-one series of potent D-amino acid oxidase (DAAO) inhibitors. J Med Chem. 2009 Jun 11;52(11):3576-85. PMID:19438227 doi:10.1021/jm900128w

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