3gep
From Proteopedia
Human hypoxanthine guanine phosphoribosyltranserfase in complex with (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)guanine
Template:ABSTRACT PUBMED 19527031
About this Structure
3GEP is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Keough DT, Hockova D, Holy A, Naesens LM, Skinner-Adams TS, Jersey J, Guddat LW. Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: a new class of antimalarial therapeutics. J Med Chem. 2009 Jul 23;52(14):4391-9. PMID:19527031 doi:10.1021/jm900267n
Page seeded by OCA on Wed Aug 19 13:07:14 2009
Categories: Homo sapiens | Hypoxanthine phosphoribosyltransferase | Guddat, L W. | Jersey, J. | Keough, D T. | Acetylation | Acyclic nucleoside phosphonate | Cytoplasm | Disease mutation | Glycosyltransferase | Gout | Magnesium | Malarial chemotherapeutic | Metal-binding | Phosphoribosyltransferase | Purine salvage | Purine salvage pathway | Transferase
