3hrf

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Image:3hrf.jpg

Template:STRUCTURE 3hrf

Crystal structure of Human PDK1 kinase domain in complex with an allosteric activator bound to the PIF-pocket

Template:ABSTRACT PUBMED 19718043

About this Structure

3HRF is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hindie V, Stroba A, Zhang H, Lopez-Garcia LA, Idrissova L, Zeuzem S, Hirschberg D, Schaeffer F, Jorgensen TJ, Engel M, Alzari PM, Biondi RM. Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1. Nat Chem Biol. 2009 Oct;5(10):758-64. Epub 2009 Aug 30. PMID:19718043 doi:10.1038/nchembio.208

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