3pp7

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Template:STRUCTURE 3pp7

Contents

Crystal structure of Leishmania mexicana pyruvate kinase in complex with the drug suramin, an inhibitor of glycolysis.

Template:ABSTRACT PUBMED 21733839

About this Structure

3pp7 is a 2 chain structure with sequence from Leishmania mexicana. Full crystallographic information is available from OCA.

See Also

Reference

  • Morgan HP, McNae IW, Nowicki MW, Zhong W, Michels PA, Auld DS, Fothergill-Gilmore LA, Walkinshaw MD. The trypanocidal drug suramin and other trypan blue mimetics are inhibitors of pyruvate kinases and bind to the adenosine site. J Biol Chem. 2011 Jul 5. PMID:21733839 doi:10.1074/jbc.M110.212613

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