1js3

From Proteopedia

proteopedia linkproteopedia link

spinqualitylabelsall models PDB ID 1js3 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
1js3, resolution 2.25Å ()
Ligands:	, ,
Activity:	Aromatic-L-amino-acid decarboxylase, with EC number 4.1.1.28
Related:	1js6
Structural annotation: Resources: CATH : 1Js3A01, 1Js3A03, 1Js3A02, 1Js3B03, 1Js3B02, 1Js3B01 InterPro : Ipr010977, Ipr002129, Ipr015421, Ipr015424, Ipr015422 Pfam : PF00282 SCOP : d1js3a_, d1js3b_ UniProt : P80041
Functional annotation: Biological process: carboxylic acid metabolic process amino acid and derivative metabolic process catecholamine biosynthetic process Molecular function: lyase activity carboxy-lyase activity catalytic activity pyridoxal phosphate binding aromatic-L-amino-acid decarboxylase activity
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, RCSB, PDBsum
Coordinates:	save as pdb, mmCIF, xml

Contents 1 Crystal structure of dopa decarboxylase in complex with the inhibitor carbidopa 2 About this Structure 3 See Also 4 Reference

Crystal structure of dopa decarboxylase in complex with the inhibitor carbidopa

Template:ABSTRACT PUBMED 11685243

About this Structure

1js3 is a 2 chain structure with sequence from Sus scrofa. Full crystallographic information is available from OCA.

See Also

• DOPA decarboxylase
• User:Brian Hernandez/DOPA Decarboxylase

Reference

• Burkhard P, Dominici P, Borri-Voltattorni C, Jansonius JN, Malashkevich VN. Structural insight into Parkinson's disease treatment from drug-inhibited DOPA decarboxylase. Nat Struct Biol. 2001 Nov;8(11):963-7. PMID:11685243 doi:http://dx.doi.org/10.1038/nsb1101-963