3pp0

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Template:STRUCTURE 3pp0

Contents

Crystal Structure of the Kinase domain of Human HER2 (erbB2).

Template:ABSTRACT PUBMED 21454582

About this Structure

3pp0 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Aertgeerts K, Skene R, Yano J, Sang BC, Zou H, Snell G, Jennings A, Iwamoto K, Habuka N, Hirokawa A, Ishikawa T, Tanaka T, Miki H, Ohta Y, Sogabe S. Structural Analysis of the Mechanism of Inhibition and Allosteric Activation of the Kinase Domain of HER2 Protein. J Biol Chem. 2011 May 27;286(21):18756-65. Epub 2011 Mar 30. PMID:21454582 doi:10.1074/jbc.M110.206193
  • Tsou YA, Chen KC, Chang SS, Wen YR, Chen CY. A possible strategy against head and neck cancer: in silico investigation of three-in-one inhibitors. J Biomol Struct Dyn. 2012 Nov 12. PMID:23140436 doi:10.1080/07391102.2012.736773

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