4aq3

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Template:STRUCTURE 4aq3

HUMAN BCL-2 WITH PHENYLACYLSULFONAMIDE INHIBITOR

Template:ABSTRACT PUBMED 22608961

About this Structure

4aq3 is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Perez HL, Banfi P, Bertrand J, Cai ZW, Grebinski JW, Kim K, Lippy J, Modugno M, Naglich J, Schmidt RJ, Tebben A, Vianello P, Wei DD, Zhang L, Galvani A, Lombardo LJ, Borzilleri RM. Identification of a phenylacylsulfonamide series of dual Bcl-2/Bcl-xL antagonists. Bioorg Med Chem Lett. 2012 Jun 15;22(12):3946-50. Epub 2012 May 2. PMID:22608961 doi:10.1016/j.bmcl.2012.04.103

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