4g5p

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Image:4g5p.png

Template:STRUCTURE 4g5p

Crystal structure of EGFR kinase T790M in complex with BIBW2992

Template:ABSTRACT PUBMED 22888144

About this Structure

4g5p is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Solca F, Dahl G, Zoephel A, Bader G, Sanderson M, Klein C, Kraemer O, Himmelsbach F, Haaksma E, Adolf GR. Target Binding Properties and Cellular Activity of Afatinib (BIBW 2992), an Irreversible ErbB Family Blocker. J Pharmacol Exp Ther. 2012 Aug 10. PMID:22888144 doi:10.1124/jpet.112.197756

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