3ugc
From Proteopedia
Structural basis of Jak2 inhibition by the type II inhibtor NVP-BBT594
Template:ABSTRACT PUBMED 22684457
About this Structure
3ugc is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Andraos R, Qian Z, Bonenfant D, Rubert J, Vangrevelinghe E, Scheufler C, Marque F, Regnier CH, De Pover A, Ryckelynck H, Bhagwat N, Koppikar P, Goel A, Wyder L, Tavares G, Baffert F, Pissot-Soldermann C, Manley PW, Gaul C, Voshol H, Levine RL, Sellers WR, Hofmann F, Radimerski T. Modulation of activation-loop phosphorylation by JAK inhibitors is binding mode dependent. Cancer Discov. 2012 Jun;2(6):512-23. Epub 2012 May 3. PMID:22684457 doi:10.1158/2159-8290.CD-11-0324
