3lfm

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Template:STRUCTURE 3lfm

Contents

Crystal structure of the fat mass and obesity associated (FTO) protein reveals basis for its substrate specificity

Template:ABSTRACT PUBMED 20376003

Disease

Known disease associated with this structure: Obesity, associated with OMIM:[610966]

About this Structure

3LFM is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Han Z, Niu T, Chang J, Lei X, Zhao M, Wang Q, Cheng W, Wang J, Feng Y, Chai J. Crystal structure of the FTO protein reveals basis for its substrate specificity. Nature. 2010 Apr 22;464(7292):1205-9. Epub 2010 Apr 7. PMID:20376003 doi:10.1038/nature08921

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