2g30

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Template:STRUCTURE 2g30

beta appendage of AP2 complexed with ARH peptide

Template:ABSTRACT PUBMED 16516836

About this Structure

2g30 is a 3 chain structure with sequence from Homo sapiens. The April 2007 RCSB PDB Molecule of the Month feature on Clathrin by Graham T. Johnson and David S. Goodsell is 10.2210/rcsb_pdb/mom_2007_4. Full crystallographic information is available from OCA.

Reference

  • Edeling MA, Mishra SK, Keyel PA, Steinhauser AL, Collins BM, Roth R, Heuser JE, Owen DJ, Traub LM. Molecular switches involving the AP-2 beta2 appendage regulate endocytic cargo selection and clathrin coat assembly. Dev Cell. 2006 Mar;10(3):329-42. PMID:16516836 doi:10.1016/j.devcel.2006.01.016
  • Wilmann PG, Battad J, Petersen J, Wilce MC, Dove S, Devenish RJ, Prescott M, Rossjohn J. The 2.1A crystal structure of copGFP, a representative member of the copepod clade within the green fluorescent protein superfamily. J Mol Biol. 2006 Jun 16;359(4):890-900. Epub 2006 Apr 25. PMID:16697009 doi:10.1016/j.jmb.2006.04.002
  • Traub LM. Tickets to ride: selecting cargo for clathrin-regulated internalization. Nat Rev Mol Cell Biol. 2009 Sep;10(9):583-96. PMID:19696796 doi:10.1038/nrm2751

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