2ow9

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 2ow9

Contents 1 Crystal structure analysis of the MMP13 catalytic domain in complex with specific inhibitor 2 About this Structure 3 See Also 4 Reference

Crystal structure analysis of the MMP13 catalytic domain in complex with specific inhibitor

Template:ABSTRACT PUBMED 17623656

About this Structure

2ow9 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Matrix metalloproteinase

Reference

• Johnson AR, Pavlovsky AG, Ortwine DF, Prior F, Man CF, Bornemeier DA, Banotai CA, Mueller WT, McConnell P, Yan C, Baragi V, Lesch C, Roark WH, Wilson M, Datta K, Guzman R, Han HK, Dyer RD. Discovery and characterization of a novel inhibitor of matrix metalloprotease-13 that reduces cartilage damage in vivo without joint fibroplasia side effects. J Biol Chem. 2007 Sep 21;282(38):27781-91. Epub 2007 Jul 10. PMID:17623656 doi:http://dx.doi.org/10.1074/jbc.M703286200