3h42
From Proteopedia
Contents |
Crystal structure of PCSK9 in complex with Fab from LDLR competitive antibody
Template:ABSTRACT PUBMED 19443683
About this Structure
3h42 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Chan JC, Piper DE, Cao Q, Liu D, King C, Wang W, Tang J, Liu Q, Higbee J, Xia Z, Di Y, Shetterly S, Arimura Z, Salomonis H, Romanow WG, Thibault ST, Zhang R, Cao P, Yang XP, Yu T, Lu M, Retter MW, Kwon G, Henne K, Pan O, Tsai MM, Fuchslocher B, Yang E, Zhou L, Lee KJ, Daris M, Sheng J, Wang Y, Shen WD, Yeh WC, Emery M, Walker NP, Shan B, Schwarz M, Jackson SM. A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates. Proc Natl Acad Sci U S A. 2009 May 14. PMID:19443683
Categories: Homo sapiens | Piper, D E. | Romanow, W G. | Thibault, S T. | Tsai, M M. | Walker, N P.C. | Yang, E. | Autocatalytic cleavage | Cholesterol metabolism | Disease mutation | Disulfide bond | Glycoprotein | Hydrolase | Hydrolase-immune system complex | Lipid metabolism | Phosphoprotein | Protease | Protein fab complex | Secreted | Serine protease | Steroid metabolism | Zymogen
