3vhv

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Template:STRUCTURE 3vhv

Mineralocorticoid receptor ligand-binding domain with non-steroidal antagonist

Template:ABSTRACT PUBMED 22074142

About this Structure

3vhv is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hasui T, Matsunaga N, Ora T, Ohyabu N, Nishigaki N, Imura Y, Igata Y, Matsui H, Motoyaji T, Tanaka T, Habuka N, Sogabe S, Ono M, Siedem CS, Tang TP, Gauthier C, De Meese LA, Boyd SA, Fukumoto S. Identification of Benzoxazin-3-one Derivatives as Novel, Potent, and Selective Nonsteroidal Mineralocorticoid Receptor Antagonists. J Med Chem. 2011 Dec 22;54(24):8616-31. Epub 2011 Nov 29. PMID:22074142 doi:10.1021/jm2011645

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