3q4c

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Image:3q4c.png

Template:STRUCTURE 3q4c

Crystal Structure of Wild Type BRAF kinase domain in complex with organometallic inhibitor CNS292

Template:ABSTRACT PUBMED 19371126

About this Structure

3q4c is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Xie P, Streu C, Qin J, Bregman H, Pagano N, Meggers E, Marmorstein R. The crystal structure of BRAF in complex with an organoruthenium inhibitor reveals a mechanism for inhibition of an active form of BRAF kinase. Biochemistry. 2009 Jun 16;48(23):5187-98. PMID:19371126 doi:10.1021/bi802067u

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