3tcp
From Proteopedia
Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC569
Template:ABSTRACT PUBMED 22662287
About this Structure
3tcp is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Liu J, Yang C, Simpson C, Deryckere D, Van Deusen A, Miley MJ, Kireev D, Norris-Drouin J, Sather S, Hunter D, Korboukh VK, Patel HS, Janzen WP, Machius M, Johnson GL, Earp HS, Graham DK, Frye SV, Wang X. Discovery of Novel Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia. ACS Med Chem Lett. 2012 Feb 9;3(2):129-134. PMID:22662287
Categories: Homo sapiens | Receptor protein-tyrosine kinase | DeRyckere, D. | Deusen, A Van. | Earp, H S. | Frye, S. | Graham, D K | Hunter, D. | Janzen, W P. | Johnson, G. | Kireev, D B. | Liu, J. | Machius, M. | Miley, M. | Norris-Drouin, J. | Patel, H S. | Sather, S. | Simpson, C. | Wang, X. | Yang, C. | Acute lymphoblastic leukemia | Rational structure-based drug design | Transferase-transferase inhibitor complex | Tyrosine kinase
