3b8q

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Template:STRUCTURE 3b8q

Contents

Crystal structure of the VEGFR2 kinase domain in complex with a naphthamide inhibitor

Template:ABSTRACT PUBMED 18324761

About this Structure

3b8q is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Harmange JC, Weiss MM, Germain J, Polverino AJ, Borg G, Bready J, Chen D, Choquette D, Coxon A, Demelfi T, Dipietro L, Doerr N, Estrada J, Flynn J, Graceffa RF, Harriman SP, Kaufman S, La DS, Long A, Martin MW, Neervannan S, Patel VF, Potashman M, Regal K, Roveto PM, Schrag ML, Starnes C, Tasker A, Teffera Y, Wang L, White RD, Whittington DA, Zanon R. Naphthamides as novel and potent vascular endothelial growth factor receptor tyrosine kinase inhibitors: design, synthesis, and evaluation. J Med Chem. 2008 Mar 27;51(6):1649-67. Epub 2008 Mar 7. PMID:18324761 doi:10.1021/jm701097z

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